Replication DNA.swf / DNA Replikasi.swf

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  • DNA replication begins with the "unzipping" of the parent molecule as the hydrogen bonds between the base pairs are broken.
  • Once exposed, the sequence of bases on each of the separated strands serves as a template to guide the insertion of a complementary set of bases on the strand being synthesized.
  • The new strands are assembled from deoxynucleoside triphosphates.
  • Each incoming nucleotide is covalently linked to the "free" 3' carbon atom on the pentose (figure) as
  • the second and third phosphates are removed together as a molecule of pyrophosphate (PPi).
  • The nucleotides are assembled in the order that complements the order of bases on the strand serving as the template.
  • Thus each C on the template guides the insertion of a G on the new strand, each G a C, and so on.
  • When the process is complete, two DNA molecules have been formed identical to each other and to the parent molecule.

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